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KMID : 0356919940270121734
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Korean Journal of Anesthesiology
1994 Volume.27 No. 12 p.1734 ~ p.1739
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A Comparison of The Induction Characterissics of Propofol and Thiopental on The Hypertensive Patients
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Abstract
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We have compared the cardiovascular effects during intravenous induction and endotracheal intubation with propofol or thiopental sodium on the forty hypertensive patients.
Propofol was given 2mg/kg or thiopental sodium was given 5mg/kg intravenously for induction of general anesthesia, and endotracheal intubation. The patients were allocated in two groups according to the intravenous anesthetic agents that were
administered (Group Ⅰ; 20 patients Propofol group and Group Ⅱ; 20 patients Thiopental group).
Arterial blood pressure and heart rate was recorded by automatic noninvasive blood pressure cuff (ESCORT 100/200 Medical Data Electronics. Arleta Ca. U.S.A.). Systolic, diastolic arterial blood pressure, and heart rates were recorded 1 minutes
after
endotracheal intubation. Reduction of systolic and diastolic arterial blood pressure were significantly greater after propofol (30%) than thiopental sodium administration and intubation. The change of the heart rate after propofol induction and
intubation was not significant. However, the heart rate was increased about 23% after thiopental sodium induction and intubation.
The results of this study indicate that propofol 2mg/kg intravenous induction and intubation for hypertensive surgical patient should be contribute to patient's prognosis.
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